ctcRbase

Entry Detail

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General Information

Database ID: SKCM05307 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: FBLIM1 Full Name: filamin binding LIM protein 1 Category: mRNA Synonyms: CAL|FBLP-1|FBLP1 Chromosome: chr1 Strand: + Coordinate: Start Site(bp): 15756607 End Site(bp): 15786594 Gene Summary: This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000162458 HGNC ID: HGNC:24686 Entrez Gene: 54751

Expression Profile of FBLIM1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-186-5p YES YES NO hsa-miR-24-3p YES YES NO hsa-miR-302a-3p YES YES NO hsa-miR-302b-3p YES YES NO hsa-miR-302c-3p YES YES NO hsa-miR-302d-3p YES YES NO hsa-miR-302e YES YES NO hsa-miR-335-5p YES YES YES hsa-miR-372-3p YES YES NO hsa-miR-373-3p YES YES NO hsa-miR-486-5p YES YES NO hsa-miR-520a-3p YES YES NO hsa-miR-520b YES YES NO hsa-miR-520c-3p YES YES NO hsa-miR-520d-3p YES YES NO hsa-miR-520e YES YES NO Display: