Entry Detail



General Information

Database ID:SKCM05316
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:CASC3
Full Name:CASC3, exon junction complex subunit
Category:mRNA
Synonyms:BTZ|MLN51
Chromosome:chr17
Strand:+
Coordinate:
Start Site(bp):40140318End Site(bp):40172183
Gene Summary:The product of this gene is a core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated mRNA decay (NMD). The encoded protein binds RNA and interacts with two other EJC core components. It is predominantly located in the cytoplasm, but shuttles into the nucleus where it localizes to nuclear speckles. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000108349
HGNC ID:HGNC:17040
Entrez Gene:22794



Expression Profile of CASC3 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-124-3p
YES
NO
YES
hsa-miR-125a-5p
YES
YES
NO
hsa-miR-125b-5p
YES
YES
NO
hsa-miR-128-3p
YES
YES
NO
hsa-miR-133a-3p
YES
YES
YES
hsa-miR-133b
YES
YES
YES
hsa-miR-136-5p
YES
YES
NO
hsa-miR-140-5p
YES
YES
NO
hsa-miR-141-3p
YES
YES
NO
hsa-miR-185-5p
YES
YES
NO
hsa-miR-196a-5p
YES
YES
NO
hsa-miR-196b-5p
YES
YES
NO
hsa-miR-204-5p
YES
YES
NO
hsa-miR-211-5p
YES
YES
NO
hsa-miR-216b-5p
YES
YES
NO
hsa-miR-224-5p
YES
YES
YES
hsa-miR-27a-3p
YES
YES
YES
hsa-miR-27b-3p
YES
YES
YES
hsa-miR-28-5p
YES
YES
NO
hsa-miR-300
YES
YES
NO
hsa-miR-329-3p
YES
YES
NO
hsa-miR-331-3p
YES
NO
YES
hsa-miR-33a-5p
YES
YES
YES
hsa-miR-33b-5p
YES
YES
YES
hsa-miR-362-3p
YES
YES
NO
hsa-miR-379-5p
YES
YES
NO
hsa-miR-381-3p
YES
YES
NO
hsa-miR-488-3p
YES
YES
NO
hsa-miR-491-5p
YES
YES
NO
hsa-miR-495-3p
YES
YES
NO
hsa-miR-506-3p
YES
YES
NO
hsa-miR-708-5p
YES
YES
NO
hsa-miR-802
YES
NO
YES
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