ctcRbase

Entry Detail

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General Information

Database ID: SKCM05325 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: FN3KRP Full Name: fructosamine 3 kinase related protein Category: mRNA Synonyms: FN3KL Chromosome: chr17 Strand: + Coordinate: Start Site(bp): 82716683 End Site(bp): 82730328 Gene Summary: A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine residues (glycation). Proteins modified in this way are less active or functional. This gene encodes an enzyme which catalyzes the phosphorylation of psicosamines and ribulosamines compared to the neighboring gene which encodes a highly similar enzyme, fructosamine-3-kinase, which has different substrate specificity. The activity of both enzymes may result in deglycation of proteins to restore their function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012] External Links: Ensembl ID: ENSG00000141560 HGNC ID: HGNC:25700 Entrez Gene: 79672

Expression Profile of FN3KRP Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES NO NO hsa-miR-107 YES NO NO hsa-miR-1252-5p YES NO NO hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-191-5p YES YES NO hsa-miR-195-5p YES YES NO hsa-miR-208a-3p YES YES NO hsa-miR-208b-3p YES YES NO hsa-miR-214-3p YES NO NO hsa-miR-217 YES YES NO hsa-miR-24-3p YES YES NO hsa-miR-338-3p YES YES NO hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-424-5p YES YES NO hsa-miR-431-5p YES YES NO hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-497-5p YES YES NO Display: