ctcRbase

Entry Detail

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General Information

Database ID: SKCM05333 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: RUFY3 Full Name: RUN and FYVE domain containing 3 Category: mRNA Synonyms: RIPX|SINGAR1|ZFYVE30 Chromosome: chr4 Strand: + Coordinate: Start Site(bp): 70704204 End Site(bp): 70807315 Gene Summary: This gene encodes a RPIP8, UNC-14, and NESCA domain-containing protein that is required for maintenance of neuronal polarity. In addition, it has been implicated in mediation of gastric cancer cell migration and invasion via interaction with P21-activated kinase-1, which promotes its expression. The encoded protein localizes to F-actin-enriched invadopodia to induce formation of protrusions, thereby facilitating cell migration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016] External Links: Ensembl ID: ENSG00000018189 HGNC ID: HGNC:30285 Entrez Gene: 22902

Expression Profile of RUFY3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES YES hsa-let-7b-5p YES YES YES hsa-let-7c-5p YES YES YES hsa-let-7d-5p YES YES YES hsa-let-7e-5p YES YES YES hsa-let-7f-5p YES YES YES hsa-let-7g-5p YES YES YES hsa-let-7i-5p YES YES YES hsa-miR-125a-5p YES YES YES hsa-miR-125b-5p YES YES YES hsa-miR-128-3p YES NO YES hsa-miR-1297 YES YES NO hsa-miR-139-5p YES YES YES hsa-miR-143-3p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-194-5p YES YES NO hsa-miR-196a-5p YES YES YES hsa-miR-196b-5p YES YES YES hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-27a-3p YES YES YES hsa-miR-27b-3p YES YES YES hsa-miR-335-5p YES YES NO hsa-miR-384 YES YES NO hsa-miR-582-5p YES NO YES hsa-miR-98-5p YES YES YES Display: