ctcRbase

Entry Detail

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General Information

Database ID: SKCM05342 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: RCAN1 Full Name: regulator of calcineurin 1 Category: mRNA Synonyms: ADAPT78|CSP1|DSC1|DSCR1|MCIP1|RCN1 Chromosome: chr21 Strand: - Coordinate: Start Site(bp): 34513142 End Site(bp): 34615142 Gene Summary: The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013] External Links: Ensembl ID: ENSG00000159200 HGNC ID: HGNC:3040 Entrez Gene: 1827

Expression Profile of RCAN1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES YES hsa-miR-107 YES YES YES hsa-miR-124-3p YES YES YES hsa-miR-1271-5p YES YES NO hsa-miR-145-5p YES YES YES hsa-miR-146a-5p YES NO YES hsa-miR-146b-5p YES NO YES hsa-miR-150-5p YES YES NO hsa-miR-154-5p YES YES NO hsa-miR-155-5p YES YES NO hsa-miR-182-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-197-3p YES YES NO hsa-miR-217 YES NO YES hsa-miR-27a-3p YES YES NO hsa-miR-27b-3p YES YES NO hsa-miR-30a-5p YES YES YES hsa-miR-30b-5p YES YES YES hsa-miR-30c-5p YES YES YES hsa-miR-30d-5p YES YES YES hsa-miR-30e-5p YES YES YES hsa-miR-323a-3p YES NO YES hsa-miR-324-5p YES YES YES hsa-miR-330-3p YES NO YES hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-34a-5p YES YES YES hsa-miR-34c-5p YES YES YES hsa-miR-369-3p YES NO YES hsa-miR-371a-5p YES YES NO hsa-miR-374a-5p YES YES YES hsa-miR-374b-5p YES YES YES hsa-miR-425-5p YES YES NO hsa-miR-449a YES YES YES hsa-miR-449b-5p YES YES YES hsa-miR-506-3p YES YES NO hsa-miR-655-3p YES NO YES hsa-miR-874-3p YES YES NO hsa-miR-876-5p YES YES NO hsa-miR-96-5p YES YES NO Display: