ctcRbase

Entry Detail

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General Information

Database ID: SKCM05361 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: MDFIC Full Name: MyoD family inhibitor domain containing Category: mRNA Synonyms: HIC|MDFIC1 Chromosome: chr7 Strand: + Coordinate: Start Site(bp): 114922154 End Site(bp): 115019202 Gene Summary: This gene product is a member of a family of proteins characterized by a specific cysteine-rich C-terminal domain, which is involved in transcriptional regulation of viral genome expression. Alternative translation initiation from an upstream non-AUG (GUG), and an in-frame, downstream AUG codon, results in the production of two isoforms, p40 and p32, respectively, which have different subcellular localization; p32 is mainly found in the cytoplasm, whereas p40 is targeted to the nucleolus. Both isoforms have transcriptional regulatory activity that is attributable to the cysteine-rich C-terminal domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009] External Links: Ensembl ID: ENSG00000135272 HGNC ID: HGNC:28870 Entrez Gene: 29969

Expression Profile of MDFIC Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-130a-3p YES YES YES hsa-miR-130b-3p YES YES YES hsa-miR-132-3p YES NO YES hsa-miR-145-5p YES YES YES hsa-miR-148a-3p YES YES YES hsa-miR-148b-3p YES YES YES hsa-miR-152-3p YES YES YES hsa-miR-19a-3p YES YES YES hsa-miR-19b-3p YES YES YES hsa-miR-212-3p YES NO YES hsa-miR-216a-5p YES YES NO hsa-miR-218-5p YES YES NO hsa-miR-23a-3p YES YES YES hsa-miR-23b-3p YES YES YES hsa-miR-27a-3p YES YES NO hsa-miR-27b-3p YES YES NO hsa-miR-299-3p YES YES NO hsa-miR-301a-3p YES YES YES hsa-miR-301b-3p YES YES YES hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-369-3p YES NO YES hsa-miR-410-3p YES YES NO hsa-miR-411-5p YES YES NO hsa-miR-433-3p YES YES NO hsa-miR-448 YES YES NO hsa-miR-454-3p YES YES YES hsa-miR-495-3p YES YES NO hsa-miR-655-3p YES NO YES Display: