ctcRbase

Entry Detail

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General Information

Database ID: SKCM05406 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: MAPK3 Full Name: mitogen-activated protein kinase 3 Category: mRNA Synonyms: ERK-1|ERK1|ERT2|HS44KDAP|HUMKER1A|P44ERK1|P44MAPK|PRKM3|p44-ERK1|p44-MAPK Chromosome: chr16 Strand: - Coordinate: Start Site(bp): 30114105 End Site(bp): 30123506 Gene Summary: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000102882 HGNC ID: HGNC:6877 Entrez Gene: 5595

Expression Profile of MAPK3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-128-3p YES YES NO hsa-miR-129-2-3p YES NO YES hsa-miR-132-3p YES YES YES hsa-miR-1-3p YES YES YES hsa-miR-143-3p YES YES NO hsa-miR-15a-5p YES NO NO hsa-miR-15b-5p YES NO NO hsa-miR-16-5p YES NO NO hsa-miR-195-5p YES NO NO hsa-miR-205-5p YES NO YES hsa-miR-206 YES YES YES hsa-miR-212-3p YES YES YES hsa-miR-214-3p YES YES NO hsa-miR-424-5p YES NO NO hsa-miR-497-5p YES NO NO hsa-miR-503-5p YES YES NO hsa-miR-542-3p YES YES NO hsa-miR-613 YES YES YES Display: