ctcRbase

Entry Detail

---



General Information

Database ID: SKCM05447 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: KDSR Full Name: 3-ketodihydrosphingosine reductase Category: mRNA Synonyms: DHSR|EKVP4|FVT1|SDR35C1 Chromosome: chr18 Strand: - Coordinate: Start Site(bp): 63327726 End Site(bp): 63367510 Gene Summary: The protein encoded by this gene catalyzes the reduction of 3-ketodihydrosphingosine to dihydrosphingosine. The putative active site residues of the encoded protein are found on the cytosolic side of the endoplasmic reticulum membrane. A chromosomal rearrangement involving this gene is a cause of follicular lymphoma, also known as type II chronic lymphatic leukemia. The mutation of a conserved residue in the bovine ortholog causes spinal muscular atrophy. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000119537 HGNC ID: HGNC:4021 Entrez Gene: 2531

Expression Profile of KDSR Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES NO hsa-miR-129-5p YES NO YES hsa-miR-153-3p YES YES YES hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-17-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-195-5p YES YES YES hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-20a-5p YES YES NO hsa-miR-214-3p YES NO NO hsa-miR-216b-5p YES YES NO hsa-miR-221-3p YES YES YES hsa-miR-222-3p YES YES YES hsa-miR-224-5p YES YES NO hsa-miR-300 YES YES YES hsa-miR-320a YES YES YES hsa-miR-320b YES YES YES hsa-miR-320c YES YES YES hsa-miR-320d YES YES YES hsa-miR-340-5p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-378a-3p YES YES YES hsa-miR-381-3p YES YES YES hsa-miR-422a YES YES YES hsa-miR-424-5p YES YES YES hsa-miR-429 YES YES NO hsa-miR-448 YES NO YES hsa-miR-455-5p YES YES YES hsa-miR-485-5p YES NO YES hsa-miR-497-5p YES YES YES hsa-miR-503-5p YES NO YES hsa-miR-519d-3p YES YES NO Display: