| ncRNA Symbol: | GGA1 | | Full Name: | golgi associated, gamma adaptin ear containing, ARF binding protein 1 | | Category: | mRNA | | Synonyms: | - | | Chromosome: | chr22 | | Strand: | + | | Coordinate: | | Start Site(bp): | 37608475 | End Site(bp): | 37633564 | | | Gene Summary: | This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) protein family. Members of this family are ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] | | External Links: | |
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