ctcRbase

Entry Detail

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General Information

Database ID: SKCM05465 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: TMX4 Full Name: thioredoxin related transmembrane protein 4 Category: mRNA Synonyms: DJ971N18.2|PDIA14|TXNDC13 Chromosome: chr20 Strand: - Coordinate: Start Site(bp): 7977348 End Site(bp): 8019829 Gene Summary: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and C-terminal ASP/GLU-rich calcium binding domain. Unlike most members of this gene family, it lacks a C-terminal ER-retention sequence. The encoded protein has been shown to have reductase activity in vitro. [provided by RefSeq, Jan 2017] External Links: Ensembl ID: ENSG00000125827 HGNC ID: HGNC:25237 Entrez Gene: 56255

Expression Profile of TMX4 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-137 YES YES NO hsa-miR-140-5p YES YES NO hsa-miR-143-3p YES YES NO hsa-miR-144-3p YES YES NO hsa-miR-18a-5p YES YES NO hsa-miR-18b-5p YES YES NO hsa-miR-197-3p YES YES NO hsa-miR-219a-5p YES YES YES hsa-miR-31-5p YES YES YES hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-365a-3p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-411-5p YES YES NO hsa-miR-421 YES YES NO hsa-miR-431-5p YES YES NO hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-490-3p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-496 YES YES YES hsa-miR-7-5p YES YES NO hsa-miR-873-5p YES YES NO hsa-miR-9-5p YES YES NO Display: