ctcRbase

Entry Detail

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General Information

Database ID: SKCM05482 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: RNF213 Full Name: ring finger protein 213 Category: mRNA Synonyms: ALO17|C17orf27|KIAA1618|MYMY2|MYSTR|NET57 Chromosome: chr17 Strand: + Coordinate: Start Site(bp): 80260866 End Site(bp): 80398786 Gene Summary: This gene encodes a protein containing a C3HC4-type RING finger domain, which is a specialized type of Zn-finger that binds two atoms of zinc and is thought to be involved in mediating protein-protein interactions. The protein also contains an AAA domain, which is associated with ATPase activity. This gene is a susceptibility gene for Moyamoya disease, a vascular disorder of intracranial arteries. This gene is also a translocation partner in anaplastic large cell lymphoma and inflammatory myofibroblastic tumor cases, where a t(2;17)(p23;q25) translocation has been identified with the anaplastic lymphoma kinase (ALK) gene on chromosome 2, and a t(8;17)(q24;q25) translocation has been identified with the MYC gene on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011] External Links: Ensembl ID: ENSG00000173821 HGNC ID: HGNC:14539 Entrez Gene: 57674

Expression Profile of RNF213 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-124-3p YES YES YES hsa-miR-129-5p YES YES NO hsa-miR-130a-3p YES NO YES hsa-miR-130b-3p YES NO YES hsa-miR-132-3p YES YES NO hsa-miR-1-3p YES YES YES hsa-miR-145-5p YES YES NO hsa-miR-155-5p YES YES NO hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-190a-5p YES YES NO hsa-miR-195-5p YES YES YES hsa-miR-206 YES YES YES hsa-miR-212-3p YES YES NO hsa-miR-217 YES YES NO hsa-miR-223-3p YES YES NO hsa-miR-27a-3p YES YES NO hsa-miR-27b-3p YES YES NO hsa-miR-301a-3p YES NO YES hsa-miR-301b-3p YES NO YES hsa-miR-30a-5p YES YES NO hsa-miR-30b-5p YES YES NO hsa-miR-30c-5p YES YES NO hsa-miR-30d-5p YES YES NO hsa-miR-30e-5p YES YES NO hsa-miR-365a-3p YES YES NO hsa-miR-424-5p YES YES YES hsa-miR-454-3p YES NO YES hsa-miR-455-5p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-497-5p YES YES YES hsa-miR-506-3p YES YES NO hsa-miR-613 YES YES YES hsa-miR-874-3p YES YES NO Display: