ctcRbase

Entry Detail

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General Information

Database ID: SKCM05488 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: USP7 Full Name: ubiquitin specific peptidase 7 Category: mRNA Synonyms: HAUSP|TEF1 Chromosome: chr16 Strand: - Coordinate: Start Site(bp): 8892094 End Site(bp): 8964514 Gene Summary: The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder. [provided by RefSeq, Mar 2016] External Links: Ensembl ID: ENSG00000187555 HGNC ID: HGNC:12630 Entrez Gene: 7874

Expression Profile of USP7 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES YES NO hsa-miR-144-3p YES YES NO hsa-miR-148a-3p YES YES NO hsa-miR-148b-3p YES YES NO hsa-miR-152-3p YES YES NO hsa-miR-217 YES NO YES hsa-miR-300 YES YES NO hsa-miR-329-3p YES NO NO hsa-miR-338-3p YES YES YES hsa-miR-340-5p YES YES NO hsa-miR-346 YES YES NO hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-362-3p YES NO NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-409-5p YES NO YES hsa-miR-421 YES YES NO hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-503-5p YES YES NO hsa-miR-543 YES YES NO Display: