ctcRbase

Entry Detail

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General Information

Database ID: SKCM05498 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: L2HGDH Full Name: L-2-hydroxyglutarate dehydrogenase Category: mRNA Synonyms: C14orf160|L2HGA Chromosome: chr14 Strand: - Coordinate: Start Site(bp): 50237563 End Site(bp): 50312548 Gene Summary: This gene encodes L-2-hydroxyglutarate dehydrogenase, a FAD-dependent enzyme that oxidizes L-2-hydroxyglutarate to alpha-ketoglutarate in a variety of mammalian tissues. Mutations in this gene cause L-2-hydroxyglutaric aciduria, a rare autosomal recessive neurometabolic disorder resulting in moderate to severe cognitive disability. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000087299 HGNC ID: HGNC:20499 Entrez Gene: 79944

Expression Profile of L2HGDH Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES YES hsa-let-7b-5p YES YES YES hsa-let-7c-5p YES YES YES hsa-let-7d-5p YES YES YES hsa-let-7e-5p YES YES YES hsa-let-7f-5p YES YES YES hsa-let-7g-5p YES YES YES hsa-let-7i-5p YES YES YES hsa-miR-103a-3p YES YES NO hsa-miR-107 YES YES NO hsa-miR-124-3p YES YES YES hsa-miR-1297 YES YES NO hsa-miR-140-5p YES YES NO hsa-miR-148a-3p YES YES NO hsa-miR-148b-3p YES YES NO hsa-miR-152-3p YES YES NO hsa-miR-155-5p YES YES NO hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-192-5p YES YES NO hsa-miR-194-5p YES YES NO hsa-miR-195-5p YES YES NO hsa-miR-215-5p YES YES NO hsa-miR-300 YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-383-5p YES YES NO hsa-miR-424-5p YES YES NO hsa-miR-433-3p YES YES NO hsa-miR-454-3p YES YES NO hsa-miR-487b-3p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-497-5p YES YES NO hsa-miR-506-3p YES YES NO hsa-miR-758-3p YES YES NO hsa-miR-98-5p YES YES YES Display: