ctcRbase

Entry Detail

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General Information

Database ID: SKCM05502 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: MSL3 Full Name: MSL complex subunit 3 Category: mRNA Synonyms: MSL3L1 Chromosome: chrX Strand: + Coordinate: Start Site(bp): 11758159 End Site(bp): 11775753 Gene Summary: This gene encodes a nuclear protein that is similar to the product of the Drosophila male-specific lethal-3 gene. The Drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus, the human protein is thought to play a similar function in chromatin remodeling and transcriptional regulation, and it has been found as part of a complex that is responsible for histone H4 lysine-16 acetylation. This gene can undergo X inactivation. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2, 7 and 8. [provided by RefSeq, Jul 2010] External Links: Ensembl ID: ENSG00000005302 HGNC ID: HGNC:7370 Entrez Gene: 10943

Expression Profile of MSL3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-132-3p YES YES NO hsa-miR-155-5p YES YES NO hsa-miR-197-3p YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-21-5p YES YES NO hsa-miR-299-3p YES YES NO hsa-miR-451a YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-496 YES YES NO hsa-miR-590-5p YES YES NO Display: