ctcRbase

Entry Detail

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General Information

Database ID: SKCM05503 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: NPTX2 Full Name: neuronal pentraxin 2 Category: mRNA Synonyms: NARP|NP-II|NP2 Chromosome: chr7 Strand: + Coordinate: Start Site(bp): 98617297 End Site(bp): 98629868 Gene Summary: This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD. [provided by RefSeq, Feb 2009] External Links: Ensembl ID: ENSG00000106236 HGNC ID: HGNC:7953 Entrez Gene: 4885

Expression Profile of NPTX2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1271-5p YES YES YES hsa-miR-128-3p YES YES YES hsa-miR-182-5p YES NO YES hsa-miR-191-5p YES YES NO hsa-miR-27a-3p YES YES NO hsa-miR-27b-3p YES YES NO hsa-miR-326 YES YES NO hsa-miR-330-5p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-96-5p YES YES YES Display: