ctcRbase

Entry Detail

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General Information

Database ID: SKCM05558 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: SMAD3 Full Name: SMAD family member 3 Category: mRNA Synonyms: HSPC193|HsT17436|JV15-2|LDS1C|LDS3|MADH3 Chromosome: chr15 Strand: + Coordinate: Start Site(bp): 67063763 End Site(bp): 67195195 Gene Summary: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis. [provided by RefSeq, Apr 2009] External Links: Ensembl ID: ENSG00000166949 HGNC ID: HGNC:6769 Entrez Gene: 4088

Expression Profile of SMAD3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-129-2-3p YES NO YES hsa-miR-143-3p YES NO YES hsa-miR-145-5p YES YES YES hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-195-5p YES YES YES hsa-miR-214-3p YES NO NO hsa-miR-216a-5p YES NO YES hsa-miR-216b-5p YES NO YES hsa-miR-23a-3p YES YES YES hsa-miR-23b-3p YES YES YES hsa-miR-323a-3p YES NO YES hsa-miR-326 YES YES NO hsa-miR-330-5p YES YES NO hsa-miR-371a-5p YES YES NO hsa-miR-424-5p YES YES YES hsa-miR-490-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-497-5p YES YES YES hsa-miR-663a YES NO NO hsa-miR-744-5p YES NO NO Display: