ctcRbase

Entry Detail

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General Information

Database ID: SKCM05570 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: MAT1A Full Name: methionine adenosyltransferase 1A Category: mRNA Synonyms: MAT|MATA1|SAMS|SAMS1 Chromosome: chr10 Strand: - Coordinate: Start Site(bp): 80271820 End Site(bp): 80289684 Gene Summary: This gene catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. The encoded protein is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in this gene are associated with methionine adenosyltransferase deficiency. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000151224 HGNC ID: HGNC:6903 Entrez Gene: 4143

Expression Profile of MAT1A Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-29a-3p YES NO YES hsa-miR-29b-3p YES NO YES hsa-miR-29c-3p YES NO YES hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO Display: