ctcRbase

Entry Detail

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General Information

Database ID: SKCM05572 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: RASSF8 Full Name: Ras association domain family member 8 Category: mRNA Synonyms: C12orf2|HOJ1 Chromosome: chr12 Strand: + Coordinate: Start Site(bp): 25959029 End Site(bp): 26079892 Gene Summary: This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011] External Links: Ensembl ID: ENSG00000123094 HGNC ID: HGNC:13232 Entrez Gene: 11228

Expression Profile of RASSF8 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p NO YES YES hsa-miR-107 NO YES YES hsa-miR-1271-5p NO YES YES hsa-miR-137 NO YES YES hsa-miR-138-5p NO YES YES hsa-miR-141-3p NO YES YES hsa-miR-148a-3p NO YES YES hsa-miR-148b-3p NO YES YES hsa-miR-152-3p NO YES YES hsa-miR-15a-5p NO YES YES hsa-miR-15b-5p NO YES YES hsa-miR-16-5p NO YES YES hsa-miR-181a-5p NO YES YES hsa-miR-181b-5p NO YES YES hsa-miR-181c-5p NO YES YES hsa-miR-181d-5p NO YES YES hsa-miR-195-5p NO YES YES hsa-miR-200a-3p NO YES YES hsa-miR-200b-3p NO YES YES hsa-miR-200c-3p NO YES YES hsa-miR-320a NO YES YES hsa-miR-320b NO YES YES hsa-miR-320c NO YES YES hsa-miR-320d NO YES YES hsa-miR-33a-5p NO YES YES hsa-miR-33b-5p NO YES YES hsa-miR-377-3p NO YES YES hsa-miR-424-5p NO YES YES hsa-miR-429 NO YES YES hsa-miR-497-5p NO YES YES hsa-miR-543 NO YES YES hsa-miR-96-5p NO YES YES Display: