ctcRbase

Entry Detail

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General Information

Database ID: SKCM05589 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: DCK Full Name: deoxycytidine kinase Category: mRNA Synonyms: - Chromosome: chr4 Strand: + Coordinate: Start Site(bp): 70992538 End Site(bp): 71030914 Gene Summary: Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000156136 HGNC ID: HGNC:2704 Entrez Gene: 1633

Expression Profile of DCK Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-128-3p YES YES NO hsa-miR-134-5p YES YES NO hsa-miR-141-3p YES YES NO hsa-miR-154-5p YES YES NO hsa-miR-155-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-194-5p YES YES NO hsa-miR-200a-3p YES YES NO hsa-miR-224-5p YES YES NO hsa-miR-27a-3p YES YES NO hsa-miR-27b-3p YES YES NO hsa-miR-300 YES YES NO hsa-miR-361-5p YES YES NO hsa-miR-370-3p YES YES NO hsa-miR-376c-3p YES YES NO hsa-miR-378a-3p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-411-5p YES YES NO hsa-miR-422a YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-7-5p YES YES NO Display: