Entry Detail



General Information

Database ID:SKCM05615
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:VPS45
Full Name:vacuolar protein sorting 45 homolog
Category:mRNA
Synonyms:H1|H1VPS45|SCN5|VPS45A|VPS45B|VPS54A|VSP45|VSP45A
Chromosome:chr1
Strand:+
Coordinate:
Start Site(bp):150067293End Site(bp):150145327
Gene Summary:Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec1 domain family, and shows a high degree of sequence similarity to mouse, rat and yeast Vps45. The exact function of this gene is not known, but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins, including inflammatory mediators. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2013]
External Links:
Ensembl ID:ENSG00000136631
HGNC ID:HGNC:14579
Entrez Gene:11311



Expression Profile of VPS45 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-122-5p
YES
YES
NO
hsa-miR-129-5p
YES
YES
NO
hsa-miR-135a-5p
YES
YES
NO
hsa-miR-135b-5p
YES
YES
NO
hsa-miR-1-3p
YES
YES
YES
hsa-miR-143-3p
YES
YES
NO
hsa-miR-148a-3p
YES
YES
NO
hsa-miR-148b-3p
YES
YES
NO
hsa-miR-152-3p
YES
YES
NO
hsa-miR-154-5p
NO
YES
YES
hsa-miR-206
YES
YES
YES
hsa-miR-218-5p
YES
YES
NO
hsa-miR-24-3p
YES
YES
NO
hsa-miR-320a
YES
YES
NO
hsa-miR-320b
YES
YES
NO
hsa-miR-320c
YES
YES
NO
hsa-miR-320d
YES
YES
NO
hsa-miR-326
YES
YES
NO
hsa-miR-330-5p
YES
YES
NO
hsa-miR-491-5p
YES
YES
NO
hsa-miR-494-3p
YES
YES
NO
hsa-miR-599
YES
YES
NO
hsa-miR-613
YES
YES
YES
hsa-miR-876-5p
YES
YES
NO
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