ctcRbase

Entry Detail

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General Information

Database ID: SKCM05626 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: CABLES1 Full Name: Cdk5 and Abl enzyme substrate 1 Category: mRNA Synonyms: CABL1|CABLES|HsT2563|IK3-1 Chromosome: chr18 Strand: + Coordinate: Start Site(bp): 23134564 End Site(bp): 23260467 Gene Summary: This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] External Links: Ensembl ID: ENSG00000134508 HGNC ID: HGNC:25097 Entrez Gene: 91768

Expression Profile of CABLES1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES NO YES hsa-miR-106b-5p YES NO YES hsa-miR-1271-5p YES YES YES hsa-miR-128-3p YES NO YES hsa-miR-145-5p YES NO YES hsa-miR-17-5p YES NO YES hsa-miR-199a-3p YES NO YES hsa-miR-199b-3p YES NO YES hsa-miR-20a-5p YES NO YES hsa-miR-20b-5p YES NO YES hsa-miR-218-5p YES NO YES hsa-miR-329-3p YES YES NO hsa-miR-340-5p YES NO YES hsa-miR-362-3p YES YES NO hsa-miR-376c-3p YES NO YES hsa-miR-519d-3p YES NO YES hsa-miR-93-5p YES NO YES hsa-miR-96-5p YES YES YES Display: