ctcRbase

Entry Detail

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General Information

Database ID: SKCM05630 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: GLI3 Full Name: GLI family zinc finger 3 Category: mRNA Synonyms: ACLS|GCPS|GLI3-190|GLI3FL|PAP-A|PAPA|PAPA1|PAPB|PHS|PPDIV Chromosome: chr7 Strand: - Coordinate: Start Site(bp): 41960950 End Site(bp): 42237870 Gene Summary: This gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000106571 HGNC ID: HGNC:4319 Entrez Gene: 2737

Expression Profile of GLI3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES YES YES hsa-miR-140-5p YES YES YES hsa-miR-143-3p YES YES YES hsa-miR-186-5p YES YES NO hsa-miR-18a-5p YES YES NO hsa-miR-18b-5p YES YES NO hsa-miR-200b-3p YES YES YES hsa-miR-200c-3p YES YES YES hsa-miR-216b-5p YES YES NO hsa-miR-223-3p YES YES NO hsa-miR-296-3p YES YES YES hsa-miR-299-5p YES NO YES hsa-miR-429 YES YES YES hsa-miR-431-5p YES YES NO hsa-miR-489-3p YES NO YES hsa-miR-494-3p YES YES YES hsa-miR-506-3p YES YES YES hsa-miR-582-5p YES NO YES hsa-miR-7-5p YES YES YES Display: