Entry Detail



General Information

Database ID:SKCM05652
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:AATF
Full Name:apoptosis antagonizing transcription factor
Category:mRNA
Synonyms:BFR2|CHE-1|CHE1|DED
Chromosome:chr17
Strand:+
Coordinate:
Start Site(bp):36948875End Site(bp):37056871
Gene Summary:The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000275700
HGNC ID:HGNC:19235
Entrez Gene:26574



Expression Profile of AATF Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-103a-3p
YES
YES
NO
hsa-miR-107
YES
YES
NO
hsa-miR-224-5p
YES
YES
NO
Display: