Entry Detail



General Information

Database ID:SKCM05678
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:WDR73
Full Name:WD repeat domain 73
Category:mRNA
Synonyms:GAMOS|GAMOS1|HSPC264
Chromosome:chr15
Strand:-
Coordinate:
Start Site(bp):84639281End Site(bp):84654343
Gene Summary:The protein encoded by this gene is thought to contain multiple WD40 repeats. WD40 repeats are motifs that contain 40-60 amino acids, and usually end with Trp-Asp (WD). This protein is found in the cytoplasm during interphase, but accumulates at the spindle poles and astral microtubules during mitosis. Reduced expression of this gene results in abnormalities in the size and morphology of the nucleus. Mutations in this gene have been associated with Galloway-Mowat syndrome PMID: 25466283), which is a rare autosomal recessive disorder that affects both the central nervous system and kidneys. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]
External Links:
Ensembl ID:ENSG00000177082
HGNC ID:HGNC:25928
Entrez Gene:84942



Expression Profile of WDR73 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-let-7a-5p
YES
YES
NO
hsa-let-7b-5p
YES
YES
NO
hsa-let-7c-5p
YES
YES
NO
hsa-let-7d-5p
YES
YES
NO
hsa-let-7e-5p
YES
YES
NO
hsa-let-7f-5p
YES
YES
NO
hsa-let-7g-5p
YES
YES
NO
hsa-let-7i-5p
YES
YES
NO
hsa-miR-106a-5p
YES
YES
NO
hsa-miR-106b-5p
YES
YES
NO
hsa-miR-17-5p
YES
YES
NO
hsa-miR-194-5p
YES
YES
NO
hsa-miR-196a-5p
YES
YES
NO
hsa-miR-196b-5p
YES
YES
NO
hsa-miR-20a-5p
YES
YES
NO
hsa-miR-20b-5p
YES
YES
NO
hsa-miR-328-3p
YES
YES
NO
hsa-miR-519d-3p
YES
YES
NO
hsa-miR-93-5p
YES
YES
NO
hsa-miR-98-5p
YES
YES
NO
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