Entry Detail



General Information

Database ID:SKCM05679
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:STK25
Full Name:serine/threonine kinase 25
Category:mRNA
Synonyms:SOK1|YSK1
Chromosome:chr2
Strand:-
Coordinate:
Start Site(bp):241492674End Site(bp):241509730
Gene Summary:This gene encodes a member of the germinal centre kinase III (GCK III) subfamily of the sterile 20 superfamily of kinases. The encoded enzyme plays a role in serine-threonine liver kinase B1 (LKB1) signaling pathway to regulate neuronal polarization and morphology of the Golgi apparatus. The protein is translocated from the Golgi apparatus to the nucleus in response to chemical anoxia and plays a role in regulation of cell death. A pseudogene associated with this gene is located on chromosome 18. Multiple alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2012]
External Links:
Ensembl ID:ENSG00000115694
HGNC ID:HGNC:11404
Entrez Gene:10494



Expression Profile of STK25 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-101-3p
YES
YES
YES
hsa-miR-425-5p
YES
YES
NO
hsa-miR-488-3p
YES
NO
YES
hsa-miR-495-3p
YES
YES
NO
hsa-miR-543
YES
YES
NO
hsa-miR-873-5p
YES
YES
NO
hsa-miR-874-3p
YES
YES
NO
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