Entry Detail



General Information

Database ID:SKCM05693
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:ICE2
Full Name:interactor of little elongation complex ELL subunit 2
Category:mRNA
Synonyms:BRCC1|NARG2
Chromosome:chr15
Strand:-
Coordinate:
Start Site(bp):60419609End Site(bp):60479160
Gene Summary:This gene encodes a protein component of the little elongation complex (LEC), which plays a role in small nuclear RNA (snRNA) transcription. The LEC regulates snRNA transcription by enhancing both RNA Polymerase II occupancy and transcriptional elongation. The encoded protein and other LEC components have been shown to localize to Cajal bodies, which are sites of ribonucleoprotein (RNP) complex assembly. Pseudogenes of this gene have been identified on chromosomes 3 and 4. [provided by RefSeq, May 2017]
External Links:
Ensembl ID:ENSG00000128915
HGNC ID:HGNC:29885
Entrez Gene:79664



Expression Profile of ICE2 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-124-3p
YES
YES
YES
hsa-miR-141-3p
YES
YES
NO
hsa-miR-181a-5p
YES
YES
NO
hsa-miR-181b-5p
YES
YES
NO
hsa-miR-181c-5p
YES
YES
NO
hsa-miR-181d-5p
YES
YES
NO
hsa-miR-200a-3p
YES
YES
NO
hsa-miR-371a-5p
YES
YES
YES
hsa-miR-450a-5p
YES
YES
NO
hsa-miR-506-3p
YES
YES
NO
hsa-miR-543
YES
YES
NO
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