ctcRbase

Entry Detail

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General Information

Database ID: SKCM05699 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: PKP4 Full Name: plakophilin 4 Category: mRNA Synonyms: p0071 Chromosome: chr2 Strand: + Coordinate: Start Site(bp): 158456964 End Site(bp): 158682879 Gene Summary: Armadillo-like proteins are characterized by a series of armadillo repeats, first defined in the Drosophila 'armadillo' gene product, that are typically 42 to 45 amino acids in length. These proteins can be divided into subfamilies based on their number of repeats, their overall sequence similarity, and the dispersion of the repeats throughout their sequences. Members of the p120(ctn)/plakophilin subfamily of Armadillo-like proteins, including CTNND1, CTNND2, PKP1, PKP2, PKP4, and ARVCF. PKP4 may be a component of desmosomal plaque and other adhesion plaques and is thought to be involved in regulating junctional plaque organization and cadherin function. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2015] External Links: Ensembl ID: ENSG00000144283 HGNC ID: HGNC:9026 Entrez Gene: 8502

Expression Profile of PKP4 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-125a-5p YES YES YES hsa-miR-125b-5p YES YES YES hsa-miR-1297 YES YES NO hsa-miR-150-5p YES YES YES hsa-miR-183-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-192-5p YES YES YES hsa-miR-215-5p YES YES YES hsa-miR-21-5p YES YES NO hsa-miR-216a-5p YES YES YES hsa-miR-216b-5p YES YES YES hsa-miR-218-5p YES YES YES hsa-miR-223-3p YES YES YES hsa-miR-23a-3p YES YES YES hsa-miR-23b-3p YES YES YES hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-27a-3p YES YES NO hsa-miR-27b-3p YES YES NO hsa-miR-299-3p YES YES NO hsa-miR-300 YES YES NO hsa-miR-324-5p YES YES NO hsa-miR-32-5p YES YES NO hsa-miR-329-3p YES YES NO hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-34a-5p YES YES YES hsa-miR-34c-5p YES YES YES hsa-miR-361-5p YES YES YES hsa-miR-362-3p YES YES NO hsa-miR-363-3p YES YES NO hsa-miR-367-3p YES YES NO hsa-miR-371a-5p YES YES YES hsa-miR-381-3p YES YES NO hsa-miR-382-5p YES YES NO hsa-miR-449a YES YES YES hsa-miR-449b-5p YES YES YES hsa-miR-489-3p YES NO YES hsa-miR-495-3p YES YES NO hsa-miR-542-3p YES YES NO hsa-miR-590-5p YES YES NO hsa-miR-92b-3p YES YES NO Display: