ctcRbase

Entry Detail

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General Information

Database ID: SKCM05723 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: E2F6 Full Name: E2F transcription factor 6 Category: mRNA Synonyms: E2F-6 Chromosome: chr2 Strand: - Coordinate: Start Site(bp): 11444375 End Site(bp): 11466177 Gene Summary: This gene encodes a member of a family of transcription factors that play a crucial role in the control of the cell cycle. The protein encoded by this gene lacks the transactivation and tumor suppressor protein association domains found in other family members, and contains a modular suppression domain that functions in the inhibition of transcription. It interacts in a complex with chromatin modifying factors. There are pseudogenes for this gene on chromosomes 22 and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013] External Links: Ensembl ID: ENSG00000169016 HGNC ID: HGNC:3120 Entrez Gene: 1876

Expression Profile of E2F6 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES YES hsa-let-7b-5p YES YES YES hsa-let-7c-5p YES YES YES hsa-let-7d-5p YES YES YES hsa-let-7e-5p YES YES YES hsa-let-7f-5p YES YES YES hsa-let-7g-5p YES YES YES hsa-let-7i-5p YES YES YES hsa-miR-128-3p YES NO YES hsa-miR-137 YES YES YES hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-185-5p YES YES YES hsa-miR-193a-3p YES YES YES hsa-miR-193b-3p YES YES YES hsa-miR-194-5p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-216a-5p YES YES NO hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-27a-3p YES YES YES hsa-miR-27b-3p YES YES YES hsa-miR-28-5p YES YES YES hsa-miR-299-3p YES YES NO hsa-miR-31-5p YES YES NO hsa-miR-370-3p YES YES NO hsa-miR-379-5p YES YES NO hsa-miR-421 YES YES NO hsa-miR-429 YES YES NO hsa-miR-543 YES YES NO hsa-miR-708-5p YES YES YES hsa-miR-873-5p YES YES NO hsa-miR-98-5p YES YES YES Display: