Entry Detail


General Information

Database ID:SKCM05728
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:VPS37A
Full Name:VPS37A, ESCRT-I subunit
Category:mRNA
Synonyms:HCRP1|PQBP2|SPG53
Chromosome:chr8
Strand:+
Coordinate:
Start Site(bp):17246571End Site(bp):17302427
Gene Summary:This gene belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations in this gene are associated with autosomal recessive spastic paraplegia-53. A related pseudogene has been identified on chromosome 5. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2012]
External Links:
Ensembl ID:ENSG00000155975
HGNC ID:HGNC:24928
Entrez Gene:137492



Expression Profile of VPS37A Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-130a-3p
NO
YES
YES
hsa-miR-130b-3p
NO
YES
YES
hsa-miR-138-5p
NO
YES
YES
hsa-miR-143-3p
NO
YES
YES
hsa-miR-153-3p
NO
YES
YES
hsa-miR-19a-3p
NO
YES
YES
hsa-miR-19b-3p
NO
YES
YES
hsa-miR-301a-3p
NO
YES
YES
hsa-miR-301b-3p
NO
YES
YES
hsa-miR-340-5p
NO
YES
YES
hsa-miR-454-3p
NO
YES
YES
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