| ncRNA Symbol: | FGF23 |
| Full Name: | fibroblast growth factor 23 |
| Category: | mRNA |
| Synonyms: | ADHR|FGFN|HFTC2|HPDR2|HYPF|PHPTC |
| Chromosome: | chr12 |
| Strand: | - |
| Coordinate: | | Start Site(bp): | 4368227 | End Site(bp): | 4379728 |
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| Gene Summary: | This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC). [provided by RefSeq, Feb 2013] |
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