ctcRbase

Entry Detail

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General Information

Database ID: SKCM05792 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: SETX Full Name: senataxin Category: mRNA Synonyms: ALS4|AOA2|SCAR1|Sen1|bA479K20.2 Chromosome: chr9 Strand: - Coordinate: Start Site(bp): 132261356 End Site(bp): 132354985 Gene Summary: This gene encodes a protein named for its homology to the Sen1p protein of fungi which has RNA helicase activity encoded by a domain at the C-terminal end of the protein. The protein encoded by this gene contains a DNA/RNA helicase domain at its C-terminal end which suggests that it may be involved in both DNA and RNA processing. Mutations in this gene have been associated with ataxia-ocular apraxia-2 (AOA2) and an autosomal dominant form of juvenile amyotrophic lateral sclerosis (ALS4). [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000107290 HGNC ID: HGNC:445 Entrez Gene: 23064

Expression Profile of SETX Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES YES NO hsa-miR-142-5p YES NO YES hsa-miR-154-5p YES YES NO hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-21-5p YES YES NO hsa-miR-23a-3p YES NO YES hsa-miR-23b-3p YES NO YES hsa-miR-24-3p YES YES NO hsa-miR-28-3p YES NO YES hsa-miR-300 YES NO YES hsa-miR-340-5p YES YES NO hsa-miR-365a-3p YES YES NO hsa-miR-375 YES NO YES hsa-miR-381-3p YES NO YES hsa-miR-429 YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-506-3p YES YES NO hsa-miR-543 YES YES NO hsa-miR-590-5p YES YES NO hsa-miR-625-5p YES NO NO hsa-miR-653-5p YES YES NO Display: