Entry Detail



General Information

Database ID:SKCM05832
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:MYO1E
Full Name:myosin IE
Category:mRNA
Synonyms:FSGS6|HuncM-IC|MYO1C
Chromosome:chr15
Strand:-
Coordinate:
Start Site(bp):59132434End Site(bp):59372900
Gene Summary:This gene encodes a member of the nonmuscle class I myosins which are a subgroup of the unconventional myosin protein family. The unconventional myosin proteins function as actin-based molecular motors. Class I myosins are characterized by a head (motor) domain, a regulatory domain and a either a short or long tail domain. Among the class I myosins, this protein is distinguished by a long tail domain that is involved in crosslinking actin filaments. This protein localizes to the cytoplasm and may be involved in intracellular movement and membrane trafficking. Mutations in this gene are the cause of focal segmental glomerulosclerosis-6. This gene has been referred to as myosin IC in the literature but is distinct from the myosin IC gene located on chromosome 17. [provided by RefSeq, Jan 2012]
External Links:
Ensembl ID:ENSG00000157483
HGNC ID:HGNC:7599
Entrez Gene:4643



Expression Profile of MYO1E Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-101-3p
YES
YES
YES
hsa-miR-124-3p
YES
YES
YES
hsa-miR-125a-5p
YES
NO
YES
hsa-miR-125b-5p
YES
NO
YES
hsa-miR-1-3p
YES
YES
YES
hsa-miR-143-3p
YES
YES
NO
hsa-miR-144-3p
YES
YES
YES
hsa-miR-181a-5p
YES
YES
YES
hsa-miR-181b-5p
YES
YES
YES
hsa-miR-181c-5p
YES
YES
YES
hsa-miR-181d-5p
YES
YES
YES
hsa-miR-192-5p
YES
YES
NO
hsa-miR-206
YES
YES
YES
hsa-miR-215-5p
YES
YES
NO
hsa-miR-24-3p
YES
NO
YES
hsa-miR-339-5p
YES
YES
NO
hsa-miR-340-5p
YES
YES
YES
hsa-miR-506-3p
YES
YES
NO
hsa-miR-613
YES
YES
YES
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