ctcRbase

Entry Detail

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General Information

Database ID: SKCM05843 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: ITSN1 Full Name: intersectin 1 Category: mRNA Synonyms: ITSN|SH3D1A|SH3P17 Chromosome: chr21 Strand: + Coordinate: Start Site(bp): 33642400 End Site(bp): 33899861 Gene Summary: The protein encoded by this gene is a cytoplasmic membrane-associated protein that indirectly coordinates endocytic membrane traffic with the actin assembly machinery. In addition, the encoded protein may regulate the formation of clathrin-coated vesicles and could be involved in synaptic vesicle recycling. This protein has been shown to interact with dynamin, CDC42, SNAP23, SNAP25, SPIN90, EPS15, EPN1, EPN2, and STN2. Multiple transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been characterized so far. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000205726 HGNC ID: HGNC:6183 Entrez Gene: 6453

Expression Profile of ITSN1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES YES hsa-miR-107 YES YES YES hsa-miR-10a-5p YES YES YES hsa-miR-10b-5p YES YES YES hsa-miR-1224-5p YES NO YES hsa-miR-128-3p YES YES NO hsa-miR-129-5p YES YES YES hsa-miR-136-5p YES YES NO hsa-miR-150-5p YES YES YES hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-190a-5p YES NO YES hsa-miR-190b YES NO YES hsa-miR-193a-5p YES NO YES hsa-miR-194-5p YES YES YES hsa-miR-195-5p YES YES NO hsa-miR-19a-3p YES YES YES hsa-miR-19b-3p YES YES YES hsa-miR-214-3p YES YES NO hsa-miR-218-5p YES NO YES hsa-miR-224-5p YES YES NO hsa-miR-30a-5p YES YES YES hsa-miR-30b-5p YES YES YES hsa-miR-30c-5p YES YES YES hsa-miR-30d-5p YES YES YES hsa-miR-30e-5p YES YES YES hsa-miR-326 YES YES YES hsa-miR-330-5p YES YES YES hsa-miR-34a-5p YES YES YES hsa-miR-34c-5p YES YES YES hsa-miR-371a-5p YES YES NO hsa-miR-375 YES YES NO hsa-miR-424-5p YES YES NO hsa-miR-449a YES YES YES hsa-miR-449b-5p YES YES YES hsa-miR-487b-3p YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-497-5p YES YES NO hsa-miR-543 YES YES NO hsa-miR-582-5p YES NO YES hsa-miR-625-5p YES NO NO hsa-miR-92a-3p YES YES NO hsa-miR-92b-3p YES YES NO Display: