ctcRbase

Entry Detail

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General Information

Database ID: SKCM05859 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: NNT Full Name: nicotinamide nucleotide transhydrogenase Category: mRNA Synonyms: GCCD4 Chromosome: chr5 Strand: + Coordinate: Start Site(bp): 43602692 End Site(bp): 43707405 Gene Summary: This gene encodes an integral protein of the inner mitochondrial membrane. The enzyme couples hydride transfer between NAD(H) and NADP(+) to proton translocation across the inner mitochondrial membrane. Under most physiological conditions, the enzyme uses energy from the mitochondrial proton gradient to produce high concentrations of NADPH. The resulting NADPH is used for biosynthesis and in free radical detoxification. [provided by RefSeq, Sep 2016] External Links: Ensembl ID: ENSG00000112992 HGNC ID: HGNC:7863 Entrez Gene: 23530

Expression Profile of NNT Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES YES hsa-let-7b-5p YES YES YES hsa-let-7c-5p YES YES YES hsa-let-7d-5p YES YES YES hsa-let-7e-5p YES YES YES hsa-let-7f-5p YES YES YES hsa-let-7g-5p YES YES YES hsa-let-7i-5p YES YES YES hsa-miR-129-5p YES YES NO hsa-miR-1297 YES YES NO hsa-miR-139-5p YES YES NO hsa-miR-142-3p YES YES NO hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-190a-5p YES YES NO hsa-miR-190b YES YES NO hsa-miR-194-5p YES YES NO hsa-miR-196a-5p YES YES NO hsa-miR-196b-5p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-216b-5p YES YES NO hsa-miR-224-5p YES YES NO hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-335-5p YES YES NO hsa-miR-338-3p YES YES YES hsa-miR-340-5p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-382-5p YES YES NO hsa-miR-429 YES YES NO hsa-miR-431-5p YES YES NO hsa-miR-455-5p YES YES NO hsa-miR-485-5p YES YES YES hsa-miR-496 YES YES NO hsa-miR-599 YES YES NO hsa-miR-653-5p YES YES NO hsa-miR-874-3p YES YES NO hsa-miR-98-5p YES YES YES Display: