ctcRbase

Entry Detail

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General Information

Database ID: SKCM05894 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: DVL2 Full Name: dishevelled segment polarity protein 2 Category: mRNA Synonyms: - Chromosome: chr17 Strand: - Coordinate: Start Site(bp): 7225341 End Site(bp): 7234545 Gene Summary: This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000004975 HGNC ID: HGNC:3086 Entrez Gene: 1856

Expression Profile of DVL2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-125a-5p YES YES NO hsa-miR-125b-5p YES YES NO hsa-miR-128-3p YES YES YES hsa-miR-134-5p YES YES NO hsa-miR-137 YES YES YES hsa-miR-138-5p YES YES YES hsa-miR-221-3p YES YES NO hsa-miR-222-3p YES YES NO hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-27a-3p YES YES YES hsa-miR-27b-3p YES YES YES hsa-miR-300 YES YES YES hsa-miR-365a-3p YES YES NO hsa-miR-381-3p YES YES YES Display: