ctcRbase

Entry Detail

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General Information

Database ID: SKCM05925 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: EHMT1 Full Name: euchromatic histone lysine methyltransferase 1 Category: mRNA Synonyms: EHMT1-IT1|EUHMTASE1|Eu-HMTase1|FP13812|GLP|GLP1|KLEFS1|KMT1D Chromosome: chr9 Strand: + Coordinate: Start Site(bp): 137618963 End Site(bp): 137870016 Gene Summary: The protein encoded by this gene is a histone methyltransferase that methylates the lysine-9 position of histone H3. This action marks the genomic region packaged with these methylated histones for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition. Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome, also known as Kleefstra syndrome). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2017] External Links: Ensembl ID: ENSG00000181090 HGNC ID: HGNC:24650 Entrez Gene: 79813

Expression Profile of EHMT1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-18a-5p YES YES YES hsa-miR-18b-5p YES YES YES hsa-miR-217 YES YES NO hsa-miR-223-3p YES YES NO hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-375 YES YES YES hsa-miR-379-5p YES YES NO hsa-miR-421 YES YES NO hsa-miR-582-5p YES NO YES hsa-miR-599 YES YES NO hsa-miR-615-3p YES YES NO Display: