ctcRbase

Entry Detail

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General Information

Database ID: SKCM05937 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: ITGA3 Full Name: integrin subunit alpha 3 Category: mRNA Synonyms: CD49C|FRP-2|GAP-B3|GAPB3|ILNEB|MSK18|VCA-2|VL3A|VLA3a Chromosome: chr17 Strand: + Coordinate: Start Site(bp): 50055968 End Site(bp): 50090481 Gene Summary: The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function as cell surface adhesion molecules. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 3 subunit. This subunit joins with a beta 1 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. Expression of this gene may be correlated with breast cancer metastasis. [provided by RefSeq, Oct 2015] External Links: Ensembl ID: ENSG00000005884 HGNC ID: HGNC:6139 Entrez Gene: 3675

Expression Profile of ITGA3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES YES hsa-miR-124-3p YES YES YES hsa-miR-133a-3p YES YES NO hsa-miR-133b YES YES NO hsa-miR-134-5p YES YES NO hsa-miR-139-5p YES YES NO hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-185-5p YES YES NO hsa-miR-197-3p YES YES NO hsa-miR-199a-3p YES NO YES hsa-miR-199a-5p YES YES YES hsa-miR-199b-3p YES NO YES hsa-miR-199b-5p YES YES YES hsa-miR-326 YES YES NO hsa-miR-330-5p YES YES NO hsa-miR-339-5p YES YES NO hsa-miR-346 YES YES NO hsa-miR-370-3p YES YES NO hsa-miR-431-5p YES YES NO hsa-miR-455-5p YES YES NO hsa-miR-485-5p YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-506-3p YES YES NO hsa-miR-520f-3p YES NO YES Display: