ctcRbase

Entry Detail

---



General Information

Database ID: SKCM05951 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: ZNF384 Full Name: zinc finger protein 384 Category: mRNA Synonyms: CAGH1|CAGH1A|CIZ|ERDA2|NMP4|NP|TNRC1 Chromosome: chr12 Strand: - Coordinate: Start Site(bp): 6666477 End Site(bp): 6689572 Gene Summary: This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Apr 2011] External Links: Ensembl ID: ENSG00000126746 HGNC ID: HGNC:11955 Entrez Gene: 171017

Expression Profile of ZNF384 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-155-5p YES YES NO hsa-miR-185-5p YES YES NO hsa-miR-204-5p YES YES NO hsa-miR-211-5p YES YES NO hsa-miR-27b-3p YES YES NO hsa-miR-31-5p YES YES YES hsa-miR-338-3p YES YES NO hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-340-5p YES YES YES hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-409-5p YES NO YES hsa-miR-410-3p YES YES YES hsa-miR-425-5p YES YES NO hsa-miR-485-5p YES YES YES hsa-miR-495-3p YES YES NO hsa-miR-496 YES YES NO hsa-miR-532-3p YES NO YES Display: