ctcRbase

Entry Detail

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General Information

Database ID: SKCM05991 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: FBXL12 Full Name: F-box and leucine rich repeat protein 12 Category: mRNA Synonyms: Fbl12 Chromosome: chr19 Strand: - Coordinate: Start Site(bp): 9810267 End Site(bp): 9827816 Gene Summary: Members of the F-box protein family, such as FBXL12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008] External Links: Ensembl ID: ENSG00000127452 HGNC ID: HGNC:13611 Entrez Gene: 54850

Expression Profile of FBXL12 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES NO hsa-let-7b-5p YES YES NO hsa-let-7c-5p YES YES NO hsa-let-7d-5p YES YES NO hsa-let-7e-5p YES YES NO hsa-let-7f-5p YES YES NO hsa-let-7g-5p YES YES NO hsa-let-7i-5p YES YES NO hsa-miR-153-3p YES YES NO hsa-miR-299-3p YES YES NO hsa-miR-431-5p YES YES NO hsa-miR-485-5p YES YES NO hsa-miR-98-5p YES YES NO Display: