Entry Detail



General Information

Database ID:SKCM06031
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:ZNF606
Full Name:zinc finger protein 606
Category:mRNA
Synonyms:ZNF328
Chromosome:chr19
Strand:-
Coordinate:
Start Site(bp):57977053End Site(bp):58003349
Gene Summary:This gene encodes a zinc finger protein containing a Kruppel-associated box (KRAB) domain at its N-terminus, followed by contiguous C2H2 zinc finger motifs. The encoded protein is a nuclear protein that can act as a transcriptional repressor of growth factor-mediated signaling pathways in a reporter gene assay. This protein has been shown to interact with the SRY-box 9 gene product, and suppresses its transcriptional activity by inhibiting its DNA binding activity. Reduced expression of this gene promotes chondrocyte differentiation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2016]
External Links:
Ensembl ID:ENSG00000166704
HGNC ID:HGNC:25879
Entrez Gene:80095



Expression Profile of ZNF606 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-103a-3p
YES
YES
NO
hsa-miR-107
YES
YES
NO
hsa-miR-1297
YES
YES
NO
hsa-miR-141-3p
YES
YES
NO
hsa-miR-200a-3p
YES
YES
NO
hsa-miR-205-5p
YES
YES
NO
hsa-miR-26a-5p
YES
YES
NO
hsa-miR-26b-5p
YES
YES
NO
hsa-miR-300
YES
YES
NO
hsa-miR-374a-5p
YES
YES
NO
hsa-miR-374b-5p
YES
YES
NO
hsa-miR-379-5p
YES
YES
NO
hsa-miR-381-3p
YES
YES
NO
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