ctcRbase

Entry Detail

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General Information

Database ID: SKCM06105 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: LRRC8A Full Name: leucine rich repeat containing 8 VRAC subunit A Category: mRNA Synonyms: AGM5|LRRC8|SWELL1 Chromosome: chr9 Strand: + Coordinate: Start Site(bp): 128882112 End Site(bp): 128918039 Gene Summary: This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000136802 HGNC ID: HGNC:19027 Entrez Gene: 56262

Expression Profile of LRRC8A Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-10a-5p YES NO NO hsa-miR-10b-5p YES NO NO hsa-miR-125a-5p YES YES NO hsa-miR-125b-5p YES YES NO hsa-miR-129-5p YES YES NO hsa-miR-1-3p YES YES YES hsa-miR-141-3p YES YES YES hsa-miR-184 YES YES NO hsa-miR-191-5p YES NO YES hsa-miR-193a-3p YES YES YES hsa-miR-193b-3p YES YES YES hsa-miR-200a-3p YES YES YES hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-206 YES YES YES hsa-miR-208a-3p YES NO YES hsa-miR-208b-3p YES NO YES hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-425-5p YES YES NO hsa-miR-429 YES YES NO hsa-miR-491-5p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-499a-5p YES NO YES hsa-miR-543 YES NO YES hsa-miR-613 YES YES YES hsa-miR-655-3p YES NO YES hsa-miR-873-5p YES YES NO hsa-miR-96-5p YES YES NO Display: