ctcRbase

Entry Detail

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General Information

Database ID: SKCM06135 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: OPA1 Full Name: OPA1, mitochondrial dynamin like GTPase Category: mRNA Synonyms: BERHS|MGM1|MTDPS14|NPG|NTG|largeG Chromosome: chr3 Strand: + Coordinate: Start Site(bp): 193593144 End Site(bp): 193697823 Gene Summary: The protein encoded by this gene is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. The encoded protein localizes to the inner mitochondrial membrane and helps regulate mitochondrial stability and energy output. This protein also sequesters cytochrome c. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. [provided by RefSeq, Aug 2017] External Links: Ensembl ID: ENSG00000198836 HGNC ID: HGNC:8140 Entrez Gene: 4976

Expression Profile of OPA1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-128-3p YES YES YES hsa-miR-130a-3p YES YES NO hsa-miR-144-3p YES YES NO hsa-miR-146a-5p YES YES NO hsa-miR-146b-5p YES YES NO hsa-miR-148a-3p YES YES NO hsa-miR-148b-3p YES YES NO hsa-miR-152-3p YES YES NO hsa-miR-196a-5p YES YES NO hsa-miR-196b-5p YES YES NO hsa-miR-27a-3p YES YES YES hsa-miR-27b-3p YES YES YES hsa-miR-296-3p YES YES NO hsa-miR-299-3p YES YES NO hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-369-3p YES NO YES hsa-miR-376c-3p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-382-5p YES YES NO hsa-miR-485-5p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-505-3p YES YES NO hsa-miR-655-3p YES NO YES Display: