ctcRbase

Entry Detail

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General Information

Database ID: SKCM06144 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: GEMIN5 Full Name: gem nuclear organelle associated protein 5 Category: mRNA Synonyms: GEMIN-5 Chromosome: chr5 Strand: - Coordinate: Start Site(bp): 154887416 End Site(bp): 154938209 Gene Summary: This gene encodes a WD repeat protein that is a component of the survival of motor neurons (SMN) complex. The SMN complex plays a critical role in mRNA splicing through the assembly of spliceosomal small nuclear ribonucleoproteins (snRNPs), and may also mediate the assembly and transport of other classes of ribonucleoproteins. The encoded protein is the snRNA-binding component of the SMN complex. Dysregulation of this gene may play a role in alternative mRNA splicing and tumor cell motility. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011] External Links: Ensembl ID: ENSG00000082516 HGNC ID: HGNC:20043 Entrez Gene: 25929

Expression Profile of GEMIN5 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-141-3p YES NO YES hsa-miR-182-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-194-5p YES YES NO hsa-miR-200a-3p YES NO YES hsa-miR-217 YES YES NO hsa-miR-296-3p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-371a-5p YES YES NO hsa-miR-383-5p YES YES NO hsa-miR-425-5p YES YES NO hsa-miR-433-3p YES YES YES hsa-miR-488-3p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-505-3p YES YES NO hsa-miR-9-5p YES NO YES hsa-miR-96-5p YES YES NO Display: