ctcRbase

Entry Detail

---



General Information

Database ID: SKCM06155 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: GBF1 Full Name: golgi brefeldin A resistant guanine nucleotide exchange factor 1 Category: mRNA Synonyms: ARF1GEF Chromosome: chr10 Strand: + Coordinate: Start Site(bp): 102245532 End Site(bp): 102382899 Gene Summary: This gene encodes a member of the Sec7 domain family. The encoded protein is a guanine nucleotide exchange factor that regulates the recruitment of proteins to membranes by mediating GDP to GTP exchange. The encoded protein is localized to the Golgi apparatus and plays a role in vesicular trafficking by activating ADP ribosylation factor 1. The encoded protein has also been identified as an important host factor for viral replication. Multiple transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010] External Links: Ensembl ID: ENSG00000107862 HGNC ID: HGNC:4181 Entrez Gene: 8729

Expression Profile of GBF1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-140-5p YES YES NO hsa-miR-17-5p YES YES YES hsa-miR-208a-3p YES YES NO hsa-miR-208b-3p YES YES NO hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-375 YES YES NO hsa-miR-485-5p YES YES NO hsa-miR-499a-5p YES YES NO hsa-miR-519d-3p YES YES YES hsa-miR-543 YES YES NO hsa-miR-93-5p YES YES YES Display: