ctcRbase

Entry Detail

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General Information

Database ID: SKCM06185 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: ROBO1 Full Name: roundabout guidance receptor 1 Category: mRNA Synonyms: DUTT1|SAX3 Chromosome: chr3 Strand: - Coordinate: Start Site(bp): 78597240 End Site(bp): 79767815 Gene Summary: Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of this gene is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins, resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] External Links: Ensembl ID: ENSG00000169855 HGNC ID: HGNC:10249 Entrez Gene: 6091

Expression Profile of ROBO1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-129-2-3p YES NO YES hsa-miR-129-5p YES YES NO hsa-miR-130a-3p YES YES YES hsa-miR-130b-3p YES YES YES hsa-miR-132-3p YES YES NO hsa-miR-135a-5p YES YES YES hsa-miR-135b-5p YES YES YES hsa-miR-142-5p YES NO YES hsa-miR-146a-5p YES YES YES hsa-miR-146b-5p YES YES YES hsa-miR-148a-3p YES YES YES hsa-miR-148b-3p YES YES YES hsa-miR-152-3p YES YES YES hsa-miR-154-5p YES YES NO hsa-miR-204-5p YES NO YES hsa-miR-208a-3p YES YES NO hsa-miR-208b-3p YES YES NO hsa-miR-211-5p YES NO YES hsa-miR-212-3p YES YES NO hsa-miR-217 YES NO YES hsa-miR-218-5p YES YES YES hsa-miR-219a-5p YES YES YES hsa-miR-23a-3p YES YES YES hsa-miR-23b-3p YES YES YES hsa-miR-25-3p YES YES YES hsa-miR-299-5p YES NO YES hsa-miR-29a-3p YES YES YES hsa-miR-29b-3p YES YES YES hsa-miR-29c-3p YES YES YES hsa-miR-301a-3p YES YES YES hsa-miR-301b-3p YES YES YES hsa-miR-32-5p YES YES YES hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-363-3p YES YES YES hsa-miR-367-3p YES YES YES hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-376a-3p YES YES NO hsa-miR-376b-3p YES YES NO hsa-miR-376c-3p YES YES YES hsa-miR-421 YES YES NO hsa-miR-425-5p YES YES NO hsa-miR-454-3p YES YES YES hsa-miR-495-3p YES YES YES hsa-miR-499a-5p YES YES NO hsa-miR-542-3p YES YES YES hsa-miR-543 YES YES NO hsa-miR-876-5p YES YES NO hsa-miR-92a-3p YES YES YES hsa-miR-92b-3p YES YES YES Display: