ctcRbase

Entry Detail

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General Information

Database ID: SKCM06189 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: DMD Full Name: dystrophin Category: mRNA Synonyms: BMD|CMD3B|DXS142|DXS164|DXS206|DXS230|DXS239|DXS268|DXS269|DXS270|DXS272|MRX85 Chromosome: chrX Strand: - Coordinate: Start Site(bp): 31097677 End Site(bp): 33339441 Gene Summary: This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene. [provided by RefSeq, Dec 2016] External Links: Ensembl ID: ENSG00000198947 HGNC ID: HGNC:2928 Entrez Gene: 1756

Expression Profile of DMD Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES YES hsa-let-7b-5p YES YES YES hsa-let-7c-5p YES YES YES hsa-let-7d-5p YES YES YES hsa-let-7e-5p YES YES YES hsa-let-7f-5p YES YES YES hsa-let-7g-5p YES YES YES hsa-let-7i-5p YES YES YES hsa-miR-101-3p YES YES YES hsa-miR-124-3p YES YES YES hsa-miR-129-5p YES YES YES hsa-miR-139-5p YES YES YES hsa-miR-142-5p YES NO YES hsa-miR-144-3p YES YES YES hsa-miR-153-3p YES YES YES hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-186-5p YES YES YES hsa-miR-190a-5p YES YES YES hsa-miR-190b YES YES YES hsa-miR-194-5p YES YES YES hsa-miR-195-5p YES YES NO hsa-miR-204-5p YES YES NO hsa-miR-205-5p YES YES NO hsa-miR-211-5p YES YES NO hsa-miR-214-3p YES YES NO hsa-miR-300 YES YES NO hsa-miR-31-5p YES YES YES hsa-miR-320a YES YES YES hsa-miR-320b YES YES YES hsa-miR-320c YES YES YES hsa-miR-320d YES YES YES hsa-miR-340-5p YES YES YES hsa-miR-361-5p YES YES NO hsa-miR-369-3p YES NO YES hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-375 YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-382-5p YES YES NO hsa-miR-424-5p YES YES NO hsa-miR-448 YES YES YES hsa-miR-494-3p YES YES NO hsa-miR-495-3p YES NO YES hsa-miR-497-5p YES YES NO hsa-miR-506-3p YES YES YES hsa-miR-655-3p YES NO YES hsa-miR-758-3p YES YES NO hsa-miR-873-5p YES YES NO hsa-miR-98-5p YES YES YES Display: