ctcRbase

Entry Detail

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General Information

Database ID: SKCM06192 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: WASF1 Full Name: WAS protein family member 1 Category: mRNA Synonyms: SCAR1|WAVE|WAVE1 Chromosome: chr6 Strand: - Coordinate: Start Site(bp): 110099819 End Site(bp): 110180004 Gene Summary: The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000112290 HGNC ID: HGNC:12732 Entrez Gene: 8936

Expression Profile of WASF1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES YES NO hsa-miR-132-3p YES YES NO hsa-miR-140-5p YES YES YES hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-200b-3p YES YES YES hsa-miR-200c-3p YES YES YES hsa-miR-212-3p YES YES NO hsa-miR-22-3p YES YES YES hsa-miR-224-5p YES YES NO hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-24-3p YES YES NO hsa-miR-29a-3p YES YES YES hsa-miR-29b-3p YES NO YES hsa-miR-29c-3p YES YES YES hsa-miR-31-5p YES YES NO hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-34a-5p YES YES YES hsa-miR-34c-5p YES YES YES hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-411-5p YES YES NO hsa-miR-421 YES YES NO hsa-miR-429 YES YES YES hsa-miR-449a YES YES YES hsa-miR-449b-5p YES YES YES hsa-miR-496 YES YES NO hsa-miR-506-3p YES YES NO hsa-miR-543 YES YES NO hsa-miR-625-5p YES NO NO hsa-miR-873-5p YES YES NO Display: