ctcRbase

Entry Detail

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General Information

Database ID: SKCM06228 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: HK2 Full Name: hexokinase 2 Category: mRNA Synonyms: HKII|HXK2 Chromosome: chr2 Strand: + Coordinate: Start Site(bp): 74833981 End Site(bp): 74893359 Gene Summary: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells. [provided by RefSeq, Apr 2009] External Links: Ensembl ID: ENSG00000159399 HGNC ID: HGNC:4923 Entrez Gene: 3099

Expression Profile of HK2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES NO YES hsa-let-7b-5p YES NO YES hsa-let-7c-5p YES NO YES hsa-let-7d-5p YES NO YES hsa-let-7e-5p YES NO YES hsa-let-7f-5p YES NO YES hsa-let-7g-5p YES NO YES hsa-let-7i-5p YES NO YES hsa-miR-125a-5p YES YES YES hsa-miR-125b-5p YES YES YES hsa-miR-1-3p YES YES NO hsa-miR-143-3p YES YES YES hsa-miR-146b-5p YES YES NO hsa-miR-150-5p YES YES NO hsa-miR-151a-3p YES NO YES hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-182-5p YES YES NO hsa-miR-185-5p YES YES NO hsa-miR-199a-5p YES YES NO hsa-miR-199b-5p YES YES NO hsa-miR-206 YES YES NO hsa-miR-218-5p YES YES NO hsa-miR-28-5p YES YES NO hsa-miR-301a-3p YES YES NO hsa-miR-301b-3p YES YES NO hsa-miR-323a-3p YES NO YES hsa-miR-329-3p YES NO NO hsa-miR-330-3p YES NO YES hsa-miR-346 YES YES NO hsa-miR-362-3p YES NO NO hsa-miR-376c-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-543 YES YES NO hsa-miR-599 YES YES NO hsa-miR-708-5p YES YES NO hsa-miR-98-5p YES NO YES Display: