ctcRbase

Entry Detail

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General Information

Database ID: SKCM06326 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: NBR1 Full Name: NBR1, autophagy cargo receptor Category: mRNA Synonyms: 1A1-3B|IAI3B|M17S2|MIG19 Chromosome: chr17 Strand: + Coordinate: Start Site(bp): 43170481 End Site(bp): 43211689 Gene Summary: The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014] External Links: Ensembl ID: ENSG00000188554 HGNC ID: HGNC:6746 Entrez Gene: 4077

Expression Profile of NBR1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES NO hsa-miR-106b-5p YES YES NO hsa-miR-135a-5p YES YES NO hsa-miR-135b-5p YES YES NO hsa-miR-138-5p YES NO YES hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-17-5p YES YES NO hsa-miR-195-5p YES YES YES hsa-miR-197-3p YES YES NO hsa-miR-200b-3p YES YES YES hsa-miR-200c-3p YES YES YES hsa-miR-204-5p YES YES NO hsa-miR-20a-5p YES YES NO hsa-miR-20b-5p YES YES NO hsa-miR-211-5p YES YES NO hsa-miR-214-3p YES YES NO hsa-miR-22-3p YES YES NO hsa-miR-30a-5p YES YES NO hsa-miR-30b-5p YES YES NO hsa-miR-30c-5p YES YES NO hsa-miR-30d-5p YES YES NO hsa-miR-30e-5p YES YES NO hsa-miR-326 YES YES NO hsa-miR-329-3p YES NO NO hsa-miR-330-5p YES YES NO hsa-miR-339-5p YES YES NO hsa-miR-342-3p YES YES NO hsa-miR-369-3p YES NO YES hsa-miR-377-3p YES YES NO hsa-miR-424-5p YES YES YES hsa-miR-429 YES YES YES hsa-miR-431-5p YES YES NO hsa-miR-490-3p YES YES NO hsa-miR-497-5p YES YES YES hsa-miR-519d-3p YES YES NO hsa-miR-875-5p YES YES NO hsa-miR-93-5p YES YES NO Display: