Entry Detail



General Information

Database ID:SKCM06327
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:MEF2C
Full Name:myocyte enhancer factor 2C
Category:mRNA
Synonyms:C5DELq14.3|DEL5q14.3
Chromosome:chr5
Strand:-
Coordinate:
Start Site(bp):88717117End Site(bp):88904257
Gene Summary:This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. The encoded protein, MEF2 polypeptide C, has both trans-activating and DNA binding activities. This protein may play a role in maintaining the differentiated state of muscle cells. Mutations and deletions at this locus have been associated with severe cognitive disability, stereotypic movements, epilepsy, and cerebral malformation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]
External Links:
Ensembl ID:ENSG00000081189
HGNC ID:HGNC:6996
Entrez Gene:4208



Expression Profile of MEF2C Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-135a-5p
YES
YES
YES
hsa-miR-135b-5p
YES
YES
YES
hsa-miR-153-3p
YES
NO
YES
hsa-miR-182-5p
YES
YES
YES
hsa-miR-186-5p
YES
YES
NO
hsa-miR-194-5p
YES
NO
YES
hsa-miR-204-5p
YES
YES
NO
hsa-miR-211-5p
YES
YES
NO
hsa-miR-21-5p
YES
YES
YES
hsa-miR-223-3p
YES
YES
NO
hsa-miR-23a-3p
YES
YES
YES
hsa-miR-23b-3p
YES
YES
YES
hsa-miR-27a-3p
YES
YES
YES
hsa-miR-27b-3p
YES
YES
YES
hsa-miR-302a-3p
YES
YES
YES
hsa-miR-302b-3p
YES
YES
YES
hsa-miR-302c-3p
YES
YES
YES
hsa-miR-302d-3p
YES
YES
YES
hsa-miR-302e
YES
YES
YES
hsa-miR-320a
YES
YES
NO
hsa-miR-320b
YES
YES
NO
hsa-miR-320c
YES
YES
NO
hsa-miR-320d
YES
YES
NO
hsa-miR-329-3p
YES
NO
NO
hsa-miR-362-3p
YES
NO
NO
hsa-miR-372-3p
YES
YES
YES
hsa-miR-373-3p
YES
YES
YES
hsa-miR-374a-5p
YES
YES
NO
hsa-miR-410-3p
YES
YES
NO
hsa-miR-425-5p
YES
YES
YES
hsa-miR-448
YES
NO
YES
hsa-miR-452-5p
YES
NO
YES
hsa-miR-520a-3p
YES
YES
YES
hsa-miR-520b
YES
YES
YES
hsa-miR-520c-3p
YES
YES
YES
hsa-miR-520d-3p
YES
YES
YES
hsa-miR-520e
YES
YES
YES
hsa-miR-520f-3p
YES
NO
YES
hsa-miR-551a
YES
NO
YES
hsa-miR-551b-3p
YES
NO
YES
hsa-miR-590-5p
YES
YES
YES
hsa-miR-876-5p
YES
YES
NO
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